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An index reaction to 1 antimicrobial sulfonamide agent precludes future use of other antimicrobial sulfonamides due to interclass cross-reactivity of the shared arylamine groups allergenic determinant

One year earlier she recalled being told that her aminotransferase levels were high, but they had been normal on routine testing when she was 25 years old

In some embodiments, the otic formulation or composition comprises about 10% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

Interestingly, in the case of erlotinib (an EGFR inhibitor), T790M EGFR mutation-induced resistance shows a different pattern