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Supplement Wisely Consider these nutrients to support methylation: Methyl-B12 and methyl-folate TMG, NAC, riboflavin Curcumin, fish oil, Vitamins C, D, E Probiotics Note: Those with double homozygous MTHFR mutations should use low doses and avoid niacin (B3), which can slow methylation

This is why many people include these compounds in a liver-focused wellness routine

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Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons