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The catalytic parameters and substrate specificity of GPx6 are not known as the protein has not been purified yet [1, 8]

Antihypertensive therapy may be initiated preemptively, and dose modification may be required if cardiovascular events occur

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The uptake by the liver and kidneys is relatively low

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Long acting amylin receptor agonist, AZD6234, shows advantages over GLP-1 receptor agonist activation for leptin re-sensitization in a diet-induced obese (DIO) rat model