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In BV-2 microglia, berberine down-regulates lipopolysaccharide- or interferon--induced iNOS and cyclooxygenase-2 (COX-2) level, and inhibits inflammatory cytokines expression (for example IL-6, IL-1, TNF-) (Lu et al., 2010)

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The study suggests that simultaneous stimulation of GIP and GLP-1 receptors may offer a promising new treatment approach for type 2 diabetes

While animal studies have suggested numerous potential benefits of BPC-157, there is still a lack of clarity regarding its effects, side effects, and appropriate dosing in clinical settings