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Yang, T., Zelikin, A

[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations

When they are understood, theres no requirement or oversight to make sure products are sold with labels warning patients about those interactions