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70 Notably, Ulk1/2 knockdown did not affect the autophagy activity of hepatocytes but rather inhibited JNK activation by blocking the phosphorylation of MKK4/7

Immunomodulatory effects of curcumin in rheumatoid arthritis: Evidence from molecular mechanisms to clinical outcomes

Consuming antioxidants regularly will aid in eliminating the naturally occurring free radicals in the body, thus enhancing wellness by reducing the chance of non-communicable diseases like cancer, diabetes, cataracts, renal toxicity, coronary heart diseases, as well as liver and kidney diseases

For monotherapy (as a supplement for those who want to avoid medical therapy), its effects are marginal at best

This requires more pharmacological and pharmacokinetic data across the animal models to conclude

The first group was set as control group without any treatment, while mice in the following four groups were injected with complete Freunds adjuvant (20 L) in their right hind ankle joints, for establishing an AIA model