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In a key paper from 2012 it was the largest and longest-running study to date, testing 1,037 people at age 13 and 38 scientists at Duke University found a dramatic drop in intelligence among long-term marijuana users suggestive of a neurotoxic effect of cannabis on the adolescent brain, they wrote in PNAS
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The Lao people have already suffered from this contract for 25 years, said Bungon Ritthiphakdee, executive director of the Thailand-based Global Center for Good Governance in Tobacco Control
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This addiction primarily stems from the presence of nicotine, a potent psychoactive substance found in tobacco, according to an article by the Center of Addiction and Mental Health titled Nicotine Dependence. The addictive nature of tobacco leads individuals to develop a tolerance, necessitating higher amounts to achieve the same effects, ultimately reinforcing the cycle of dependence
