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By utilising non-traditional antimicrobial mechanisms like ROS generation and pH/enzyme-triggered release, these multifunctional platforms not only modulate dysbiosis and disrupt resilient biofilms, but they also achieve up to 90% wound closure in preclinical models

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To further examine C1-27 selectivity and to detect other possible targets, we synthesized a fluorescent BODIPY conjugate of a C1-27 analogue

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doi: 10.1038/ng.924 55 TedeschiPMPMJohnson-FarleyNLinHSheltonLMOogaTMackayGMGet al