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Potential Adverse Effects of L-Carnitine Published: 27 February, 2026 | 5' L-carnitine is a crucial compound in fat metabolism and can be taken as a supplement for people with a very active lifestyle or with a high metabolic demand

Introduction Growth hormone releasing hormone (GHRH) is a 44-amino acid peptide synthesized in the hypothalamus

Med Sci Res 15:671673

In a study conducted by Roxo et al., using a diabetic mouse model, metformin intervention (dose: 250 mg/kg) resulted in notable improvements in lipid metabolism and a reduction in oxidative stress

via FGF23-dependent mechanisms as well as non-FGF23-dependent mechanisms (Figure 2) (Neyra et al., 2020a)

L-Carnitine may also have antioxidant properties