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The C677T polymorphism (NCBI SNP cluster ID rs# 1801133) in MTHFR gene results in an alanine-to-valine (A222V) substitution which in turn causes a reduction in enzyme activity and subsequent elevation of plasma homocysteine [15, 16]

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It plays a critical role in maintaining the immune system's function and protecting cells from oxidative stress and damage

The cytokine storm in autoimmune flares Cytokines are the chemical messengers of the immune system