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These evolving trends introduce new patterns of nicotine dependence and complicate ongoing tobacco control efforts

6c), thus suggesting impairment of the antioxidative response system

The writing committee examined the limited research in this area and concluded that any benefits e-cigarettes may offer to help people stop smoking or stop using tobacco products needs to be clearly balanced alongside the products known and unknown potential health risks, including the known risk of long-term dependence on these products

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