Its skin-lightening reputation comes from one specific action: it shifts melanin production from eumelanin (the darker brown-black pigment) toward pheomelanin (the lighter yellow-red pigment)
PubMed Central , Clinical, Cosmetic and Investigational Dermatology , vol
Morning: Gentle cleanser Vitamin C serum (allow full absorption) Hyaluronic acid serum Niacinamide (optional, can be in moisturizer) Moisturizer Sunscreen SPF 30+ Evening: Oil cleanser (if wearing sunscreen/makeup) Gentle water-based cleanser Copper peptide serum Additional peptide serum (optional, like Matrixyl ) Heavier moisturizer or night cream This routine separates vitamin C (morning) from copper peptides (evening) while delivering multiple anti-aging mechanisms
When paired with ingredients like Glycolic acid, Niacinamide, Kojic acid and Vitamin E, Glutathione becomes even more effective while remaining skin-friendly
The quantitative values in the graphics of Fig
10.1146/annurev-bioeng-071516-044546 317 YangM.VousdenK
