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2.12.7 Fluorescence anisotropy in analysis of IDPs Fluorescence anisotropy was used to characterize the flexibility and conformational changes of IDPs in several early studies [see, e.g., aforementioned DARPP-32 analysis (Neyroz et al., 1993)]

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In addition, advancements in medical technology and innovative research approaches have made it possible to conduct clinical trials for a wider range of diseases and conditions, including rare and orphan diseases that were previously difficult to study