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SLC1A2 and SLC1A3 have also been shown to transport cysteine, but their K m values for cysteine transport are 5-fold and 10-fold higher, respectively, than that of SLC1A1 (EAAT3) (Zerangue and Kavanaugh, 1996)

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However, a recent study found that AGE-mediated crosslinks occur on the same helical Hyl sites in the collagen molecule as enzymatic crosslinks, suggesting that AGEs may impair the enzymatic crosslinking profile through steric interactions and have the potential to impact tissue mechanical properties (Hudson et al ., 2018)

Zipprich, A

PMCID: PMC3277671

Biomedicines 9(5):526