Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (which can be caused by ingestion of corrosives, extensive tumors, and conditions associated with gastric atrophy, such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy) Structural lesions leading to vitamin B 12 deficiency, including regional ileitis, ileal reactions, and malignancies Competition for vitamin B 12 by intestinal parasites or bacteria
This way, nanocarriers bring mutual benefit: they increase therapy effectiveness while decreasing the level of oxidative stress
Some even experience peeling twice in the same area
The present work was undertaken to characterize further the structural features of the tripeptide which are necessary for the activation of the GSH-receptor
Nov 2011;26(11):3609-3615
Ann Thorac Surg 103(5):1600-1605, 2017