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Freo et al., 2019a,b)

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This suggests both peptides have acceptable tolerability profiles for most users, though individual responses vary widely

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GH directly binds to growth hormone receptors (GHR) expressed in virtually all tissues, triggering JAK-STAT signaling pathways, MAPK cascades, and other intracellular signals that regulate gene transcription, protein synthesis, lipolysis, and other metabolic processes