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This is the area that typically shows the most degeneration and is the epicenter of the pain
This phenomenon can be caused by the fact that the released elemental mercury can be re-oxidized in the intracellular compartment by several enzymes, such as catalase [120,121] and re-enter the catalytic GSH-depleting cycle, ultimately leading to a displacement of the intracellular redox potential towards less negative, pro-apoptotic or necrotic values