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J Biol Chem 260:32753280 Thomas DD, Ridnour LA, Isenberg JS, Flores-Santana W, Switzer CH, Donzelli S, Hussain P, Vecoli C, Paolocci N, Ambs S, Colton CA, Harris CC, Roberts DD, Wink DA (2008) The chemical biology of nitric oxide: implications in cellular signaling

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Melanogenesis is a process by which the skins pigment cells (melanocytes) produce the hormone -MSH naturally causes the skin's pigment (melanin)

This spiral of damage will continue unless the free radical is neutralised

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