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Performance improvements stem from enhanced recovery capacity rather than direct performance enhancement
While the implications for SARM1 in regulating axonal fate are well-established, the sensing mechanisms of this protein complex toward NAD + , NMN, or even possibly toward other NAD + metabolites are not fully understood, and may suggest that also the other NAD + metabolites could regulate more biological processes than initially thought 54
Instead, it appears to modulate activity across multiple neurotransmitter systems GABA, NMDA, opioid-related pathways supporting deeper sleep architecture and stress resilience
Kim JH, Kim HS, Kim BJ, Lee J, Jang HJ
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