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10.1016/j.ntt.2013.01.004 9

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J Mol Biol 407:261272

pmid:36269889 25

PMID: 2859636

Immediate receptor binding (seconds to minutes), intracellular signaling cascade propagation (minutes to hours), gene expression changes (hours to days), protein synthesis and accumulation (days to weeks), cellular and tissue-level effects (weeks to months)