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Present practice is informed by animal studies, off-label veterinary guidelines, and clinical experience, thus treatment must be under veterinary guidance, always

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J Am Coll Surg 235:894904 Abdelmoaty WF, Dunst CM, Filicori F, Zihni AM, Davila-Bradley D, Reavis KM, Swanstrom LL, DeMeester SR (2019) Combination of surgical technique and bioresorbable mesh reinforcement of the crural repair leads to low early hernia recurrence rates with laparoscopic paraesophageal hernia repair

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The first to be approved for this indication was liraglutide (Saxenda) in 2014, followed by semaglutide (Wegovy) in 2021 and tirzepatide (Zepbound