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The studies in models investigating antifatigue and stress-protective effects indicate a possible relation to traditional medicinal use

Ethics declarations Competing interests L.H

Contributing to inflammation and redness, it is also possible that the loss of IGF-1 may increase inflammation since IGF-I inhibits actions on inflammatory and Th1-mediated cellular immune responses through stimulation of IL-10 production in T cells

Because preclinical reports describe activity on fat-cell metabolism without stimulating IGF-1 production, AOD-9604 is studied as a way to separate GH's metabolic effects from its growth-promoting effects

We also thank Jeffrey Price for his advice and continued support

It does not add anything foreign to the body