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First, our analytical methods were limited in detecting and quantifying larger biomolecules, restricting comprehensive assessments of certain pathways, particularly lipid metabolism

It should be noted that in certain cell types or cell lines, inhibition of GPX4 fails to induce ferroptosis, suggesting the existence of alternative mechanisms

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Nat Med (2007) 13:10429

This is among the broadest gene-modulatory effects of any known peptide