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First-line pharmacologic therapy typically includes TCAs such as amitriptyline, doxepin, and imipramine, which are often used for their analgesic properties in the management of neuropathic pain

Lifestyle boosts: Protein, omega-3s, good sleep, cooler showers, and a bedside humidifier help skin hold water

Dynamic metabolic-immune networks, mapped through single-cell metabolomics and spatial transcriptomics, will reveal how gut-derived metabolites sway microglial lipid metabolism or how senescent astrocytes hijack the PPP to resist apoptosis

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SODs administration has also been reported to alleviate inflammatory, infectious, respiratory, metabolic and cardiovascular diseases and genitourinary and fertility disorders, raising the question of its mechanism of action in these diverse situations

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