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as a result, the protein of interest attached to the GST will stick to the beads, isolating the protein from the rest of those in solution

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Cystinosis stands as a prototypic disorder for a subgroup of lysosomal storage diseases caused by defective lysosomal transporters [2]

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These hypoxic episodes are followed by rapid reoxygenation, which triggers a surge in the production of ROS through mechanisms such as mitochondrial dysfunction and activation of NADPH oxidase pathways (Stanek et al., 2021)