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Bilirubin metabolism and its application in disease prevention: mechanisms and research advances

Blocking GSH synthesis in combination with JMF4073 depletes dTTP/dCTP pools to eradicate T315I-Bcr-Abl leukemia We hypothesize that reducing the GSH level to increase replication stress can render T315I-Bcr-Abl leukemia more susceptible to JMF4073 in vivo

[DOI] [PMC free article] [PubMed] [Google Scholar] 203.Ringland C., Schweig J.E., Eisenbaum M., Paris D., Ait-Ghezala G., Mullan M., Crawford F., Abdullah L., Bachmeier C

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As a stable gastrin, BPC 157 has deep cell-protective activity, can exert biological effects without a carrier, and can stably exist in gastric juice for more than 24 hours, showing good oral bioavailability