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The synthesis constitutes a formal total synthesis, since the research groups only prepared the known intermediate cobyric acid, whose chemical conversion to vitamin B 12 was previously reported
When pentadecapeptide BPC 157 was given immediately after paracetamol (g-ng range, intraperitoneally or intragastrically), in accordance with a complete absence of convulsions, BPC 157 rats commonly had all alterations markedly less expressed 24 hours after paracetamol, reduced interstitial edema (only mild) and markedly less damaged neurons, without inflammatory reaction
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