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Primarily, hypothyroidism itself adversely affects gastrointestinal physiology by diminishing gastric mucosal integrity and reducing gastric acid secretion, thereby impairing the efficient absorption of nutrients and trace elements critical for thyroid function, such as selenium, iodine, iron, zinc, and vitamin D (Shulhai et al., 2024)
This suggests that microneedling + topical treatment may be more effective than PRP for most patients
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Diets high in saturated fats and simple sugars can dramatically impair neurogenesis, learning, and memory in rodents and lower BDNF levels expression [188]
Mesenchymal stem cell therapy can reduce serum amylase and TNF- concentrations, increase serum IL-10 concentrations, reduce brain microvascular endothelial cell apoptosis, up-regulate claudin-5 levels, and reduce MMP-9 levels [57, 68]
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