10.1002/jcp.27250 J Cell Physiol
It is noteworthy that, compared to rats treated with their respective conventional drugs, animals that were administered with nanoparticle versions of CO or GSH, or their combination, exhibited a notable reduction in tissue KIM-1 and NGAL levels, as depicted in Fig
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Ferroptosis is a programmed cell death with iron-dependent accumulation of lipid peroxides, which has recently been identified in animal models of DN [155]
Astaxanthin as super-antioxidant adjunct Astaxanthin properties: Carotenoid with potent antioxidant activity (stronger than vitamin E or beta-carotene), crosses blood-retinal barrier accumulating in retina, protects photoreceptors from oxidative damage, may improve visual fatigue and accommodation
Role of HO-1 in regulating diabetic cardiomyopathy Diabetic cardiovascular disease is the microvascular and macrovascular disease of the cardiovascular system caused by diabetes, which includes coronary heart disease, diabetic cardiovascular autonomic neuropathy, and diabetic cardiomyopathy [84]