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In a trial on adult volunteers, this dose did not lead to a significant increase in serum vitamin B 12 levels when given thrice daily for one week

depending on the product, a vial can last up to three months

According to 2008 research, your body only absorbs about 1.3 percent of a 1,000 mcg oral dose and 2 percent of a 500 mcg oral dose

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But with a 2mg/mL concentration (5mL of water added), that same 4mg dose requires 2.0mL of liquid, which is an entire insulin syringe worth and creates a large, uncomfortable injection volume