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According to the substrate used for the oxidation of GSH, both forms of GPx (seleno-dependent and non seleno-dependent) can react

Mitchell, Esmond E

Monzo L, Ferrari I, Cicogna F, Tota C, Cice G, Girerd N et al (2023) Sodium-glucose co-transporter 2 inhibitors in heart failure: an updated evidence-based practical guidance for clinicians

Several factors may contribute to these discordant results, and the lack of clear and robust findings, which are listed below: 1) SIM has a complex and inexplicit pathogenesis

Given the beneficial effects of several precursors and inhibitors summarized above, these strategies may be promising for finding a therapeutic strategy for AD, either as lead molecules or in combination approaches with other classes of molecules or drugs, with several studies having been launched at the clinical level