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Archived from the original on 28 October 2021

Senescent-like microglia, in contrast, limit remyelination through SASP that involves the release of multiple inflammatory mediators, including CCL11, CXCL9, and CCL5, and increased expression of IL-2, leading to impaired remyelination in mouse models (Gross et al., 2025)

The activation of NMDA receptors permits calcium influx, leading to central sensitization and amplifying the pain signals transmitted to the brain, ultimately resulting in chronic pain ( FIGURE 2 )

Types of food ingredients

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