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The rate of hippocampal neurogenesis significantly changes on physiological or pathological influences, such as physical activity, environmental enrichment, stress, and aging

Nevertheless, certain conditions can impact the absorption or intake, hence often leading to deficiency, for example, pernicious anemia or if the individual follows a vegan diet

"Vitamin B12 or folate deficiency anaemia Complications"

Dryness or sensitivity if combined with other active ingredients that irritate the skin barrier

This safety profile supports their use in both acute and chronic treatment settings

Last reviewed: May 14, 2026 Last updated: May 14, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations