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In December 2024, the FDA issued warning letters to several companies selling peptide products online, citing compounds such as retatrutide along with semaglutide and tirzepatide being marketed under research use only disclaimers while appearing to target consumers seeking weight-loss or performance benefits
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Baskaran, A.B., E
Chronic glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism desensitizes adipocyte GIPR activity mimicking functional GIPR antagonism
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