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Rushing through dose increases dramatically raises the risk of severe diarrhea and discontinuation

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In addition, thioredoxin-interacting protein (TXNIP) is an important protein that mediates ROS and the NOD-like receptor protein 3 (NLRP3) inflammasome (78)

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[Google Scholar] Dickinson DA, Forman HJ

(2) Urban T et al. (2006). Functional Genetic Diversity in the High-Affinity Carnitine Transporter OCTN2 (SLC22A5). Molecular Pharmacology, 70(5), 1602-1611. doi: 10.1124/mol.106.028126