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Past Year Substance Use Disorder (SUD) and Major Depressive Episode (MDE) Status among Youths Aged 12 to 17: Percentages, 2016 The 333,000 adolescents in 2016 who had a co-occurring MDE and an SUD in the past year represent about one third (33.0 percent) of the 1.1 million adolescents who had a past year SUD (Figure 66 and Table A.29B)