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The underlying explanation remains unclear

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Carney, S

In the initial inflammatory phase, IL-1 facilitates neutrophil infiltration and macrophage activation, whereas IL-18 supports angiogenesis and epithelial cell proliferation [30]

Excipients and adjuvant peptides induce a mild immune activation: CD8 + T-cell responses were reported in 4 of 11 patients [84]

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