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This results in reduced antioxidant activity and the accumulation of misfolded proteins, sensitizing tumor cells to anoikis

10.1016/j.fct.2013.11.014 76 IsabelC.-H.Mara ngelesM.LuisG.SoniaR

Consequently, they may exhibit undefined or broad specificity and relatively high equilibrium dissociation constant (Kd) values for their targets [442]

Front Immunol 13:793096

Spironolactone reduces DHT by blocking androgen receptors, and doctors often prescribe this drug in oral form for women suffering from female pattern hair loss or even hirsutism unwanted body and facial hair growth