As the worlds populations are rapidly heading toward an aging society and human life spans are increasing, this problem will certainly be of greater magnitude in the foreseeable future
We are in the process of exploring novel agents that target STAT3 in multiple hematological malignancies like multiple myeloma
Research indicates that people with more severe or widespread acne have more significant markers of systemic oxidative stress, including GSH deficiency (as measured through blood samples)
Changes in thyroid function tests are generally not observed, despite theoretical concerns based on animal studies showing thyroid C-cell effects
AtGLR1.2 and AtGLR1.3 contribute positively to cold tolerance by promoting jasmonate accumulation, thereby activating the CBF/DREB1 (C-repeat binding factor/dehydration-responsive element-binding protein 1) signalling cascade (Zheng et al
Yes, to the IR-A isoform with 10-100 fold lower affinity than for IGF-1R