Injection techniques such as intramuscular injection require special care to avoid side effects, including potential nerve damage. Very rare but serious reactionssuch as severe allergy, difficulty breathing, chest pain, or signs of infection at the injection siterequire immediate medical attention
From a pharmacological safety perspective, the adverse effect profile of retatrutide based on Phase 1 and Phase 2 clinical trial data (including the NEJM 2023 Phase 2 trial) includes: Gastrointestinal effects: Nausea, vomiting, diarrhoea, and constipation (the most commonly reported side effects in trial participants) Injection site reactions: Redness, swelling, or discomfort at the injection site Cardiovascular effects: Increases in heart rate have been observed in trial participants [21] [22] Hypoglycaemia: Particularly relevant in individuals with diabetes or those taking insulin, sulfonylureas, or other glucose-lowering agents Potential thyroid effects: GLP-1 receptor agonists have been associated with thyroid C-cell changes in rodent studies
DOSAGE AND ADMINISTRATION: DOSAGE
Safety vs
Every infusion is administered by a registered nurse who assesses you first, so your drip matches how you feel rather than a fixed recipe
Each has distinct pros and cons
