It works primarily by increasing VEGF expression (which promotes new blood vessel growth at injury sites) and activating cell adhesion pathways that speed tissue repair
By optimizing hormonal levels, it could have a positive impact on various physiological processes, including sleep, metabolism, and mood regulation
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Sources: Institute of Medicine, Food and Nutrition Board, National Academies of Science, Dietary Reference Intakes (DRI): Recommended Dietary Allowances and Adequate Intakes , USA 2018, Mustafa Vakur Bor, Kristina M von Castel-Roberts, Gail PA Kauwell, Sally P Stabler, Robert H Allen, David R Maneval, Lynn B Bailey Ebba Nexo Daily intake of 4 to 7 g dietary vitamin B-12 is associated with steady concentrations of vitamin B-12related biomarkers in a healthy young population Am J Clin Nutr 2010 91: 3 571-577
PLP1 mutations in patients with multiple sclerosis: identification of a new mutation and potential pathogenicity of the mutations