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Mood Changes and Depression Vitamin B12 plays a key role in the production of serotonin, a neurotransmitter that helps regulate mood

The 2024 NICE guideline on B12 deficiency in over-16s is built around identifying and treating the cause, not just topping up the number

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Standard Weekly Protocols Most adults get 1000 mcg (1 mg) of Vitamin B12 weekly

This study demonstrated that, upon fasting, SREBP1c protein in the liver is rapidly degraded by E3 ubiquitin ligase ring finger protein 20 to suppress unnecessary lipogenesis

Therefore we used the same desensitisation protocol which Caballero et al