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Glass fragments from low-quality vials, rubber particulate from non-pharmaceutical stoppers, and environmental contaminants from uncontrolled fill environments are all documented sources

Reporting summary Further information on research design is available in the Nature Research Reporting Summary linked to this article

PMID 28938471

doi: 10.1097/MPG.0000000000003643

The FDA approval is important, as we currently do not understand what the long-term health risks a patient may be putting themselves at risk of are

Secondary endpoints included the proportion of participants achieving 5% and 10% body weight reduction, absolute weight change in kg, change in waist circumference, lipid parameters including total cholesterol, HDL, LDL, VLDL, triglycerides, and glycaemic variables such as HbA1c, fasting glucose, insulin, HOMA-IR, and -cell function