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A significant increase in GSSG can be seen with diabetes and age-related macular degeneration, though low total glutathione may only be seen with diabetes (Samiec 1998)

Vitamin B-12 is found in meat, eggs, dairy and fish

Bei einem Redoxgleichgewicht wird das Verhltnis von reduziertem, nicht oxidiertem Glutathion in stabiler Form zu oxidierten Glutathionprodukten im Blut gemessen

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Moreover, Band 3 protein can also be degraded by calpain [95]

Despite the clear role that a pro-oxidative shift in metabolism has in driving NSC proliferation/differentiation, it appears there is also a limit to how much ROS can be tolerated, as a number of studies have indicated that loss of superoxide dismutase (SOD) 1, 2, or 3 can bias NSC differentiation towards more astrocyte formation, decrease hippocampal neurogenesis, and impair cognitive function in irradiated mice (Rola et al., 2007