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Moreover, loliolide upregulated the expression of DP signature genes, such as alkaline phosphatase (ALP), versican, and BMP2, in HDP spheroids

They govern hormone release, immune activity, cellular repair, appetite regulation, and dozens of other physiological processes

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Sikirics team looked for this protective substance directly in gastric juice, and they found it

NOX1 (NADPH Oxidase 1, Santa Cruz Biotechnologies, Dallas, TX), NOX2 (gp91 phox, Upstate Biotech/Thermo Fisher Scientific), and HO-1 (Enzo Life Sciences, Farmingdale, NY)

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