Vitamin B12 (as Methylcobalamin) is essential for methylmalonyl-CoA mutase and methionine synthase activity, supporting fatty acid oxidation, homocysteine remethylation, and myelin maintenance
As shown in Figure 8, Palmatine (degree = 156) has the highest number of targets, followed by columbamine (degree = 143), jatrorrhizine (degree = 109), berberine (degree = 109), corydalmine (degree = 100), tetrahydropalmatine (degree = 99), -sitosterol (degree = 71) and oleanolic acid (degree = 77)
doi: 10.1136/gut.26.12.1349
doi: 10.1016/S0147-9571(99)00076-4 200
Sep 2006;112(3):213-220
Amadori A, Zamarchi R, De Silvestro G, Forza G, Cavatton G, Danieli GA, et al