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Due to neurons having a limited capacity for GSH synthesis, they must rely on astrocytes to supply precursors such as cysteine (Prez-Sala D and Pajares, 2023)

In animal models of neurodegenerative disease, activation of TGR5 receptor was neuroprotective, decreasing neuronal death and inflammatory response (Monteiro-Cardoso et al., 2021)

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Hence, most glutamine must be synthesized by glutamine synthase, a cytosolic enzyme found in most mammalian cells

The denominator for the measure would be the total number of LTCH stays discharged during the reporting period

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