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114 However, another double-blind, placebo-controlled trial failed to show a significant benefit of magnesium, 330 mg as chloride per day, over placebo in neuropathic pain, although there was a significant improvement with regards to the frequency of pain paroxysms (attacks) and emotional impact in the magnesium group

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Aspartic acid (Asp) residues are particularly prone to hydrolysis-related degradation

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1983, 411: xiii-xvii

This backs up the metabolites, worsening problems with estrogen dominance