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Angiogenesis and Wound Healing Models: In rodent excisional wound, burn, and ischemic flap models, co-administration promoted faster wound closure, greater vascularization (upregulated VEGF), increased keratinocyte and fibroblast migration (via TB-500s actin-binding effects), and superior granulation tissue formation

PMID 37060552

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Those on 10mg lost 21.4%

4.3 Strength of evidence and research gaps A systematic evaluation of available evidence reveals varying quality levels that inform confidence in EED reproductive toxicity conclusions