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This observation has special significance for the TM/SC because changes in ECM composition, especially an increase in fibronectin expression, are associated with increased IOP and the development of POAG

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Altex 2020, 37 (4), 652664

The extracellular matrix breakdown Beyond collagen and elastin, the extracellular matrix (ECM) contains glycosaminoglycans (GAGs), proteoglycans, and structural glycoproteins that maintain skin hydration, volume, and smooth texture

Figure 1: Changes in fall latency during the rotarod test across the three different experimental groups

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